Clinical Trials
The San Diego Cancer Center will
support, promote and participate in a wide variety of clinical
trials, for nearly all types and stages of cancer. Clinical
trials play a pivotal role in the development of new cancer
treatments.
Clinical trials are carefully designed and controlled research
studies in which new drugs and /or treatment options are being
tested on patients. The goal of these new research studies
is to find more effective and safer ways to treat patients
with cancer.
Participants receive high-quality
cancer care and will be among the first to benefit if a new
approach is proven to work. The study results help oncology
specialists to develop better ways to diagnose, treat, and
prevent cancer. All clinical trials are subjected to strict
protocols to ensure the best possible outcome for participating
patients, while their safety, privacy and well being are protected.
Clinical trials may test new drugs, new combinations of drugs
we already use or new dosages, new approaches to surgery or
radiation, or new methods of treatment, such as gene therapy,
vaccine therapy and antiangiogenesis therapy.
Myths
Despite all the safety guaranties there still exists some
hesitation among patients whether to participate in clinical
trials or not. This hesitation is mostly based on a lack of
information. Some people are afraid to become a ‘guinea pig’
for experimental research studies. Others don’t want to be
part of the group of patients in the study that is treated
with a placebo, instead of the new experimental drug or treatment
that the other half of the group is receiving.
But that is not how clinical trials work. Placebos are almost
never used in studies in which new treatments are being tested.
Clinical trials are often designed to compare a specific treatment
that is currently seen as the best available with a new treatment
or drug that the study’s investigators believe is even better
or safer. From the patient’s point of view participation in
clinical trials offer high quality, state-of-the-art technology
and new treatment options. Frequently clinical trials utilize
novel, low toxicity drugs to augment conventional chemotherapy.
Access to these trials adds promise and hope to those challenged
with disease and contributes to the rapidly evolving progress
toward definitive, low toxicity solutions to cancer.
Discovery
One of the successes largely attributable
to clinical trials is the discovery in breast cancer that
lumpectomy plus radiation is as effective as mastectomy for
many women with breast cancer. This discovery prevents thousands
of women every year from undergoing total breast removal.
Despite the importance of clinical trials only about 3-5%
of patients with cancer are enrolled in clinical trials. San
Diego Cancer Center is committed to increasing the number
of patients who are enrolled in clinical trials, as they present
an opportunity for patients with cancer to receive the best
possible care.
Listed here are the clinical
trials our Cancer Center is presently conducting (programs
for prostate and brain tumors are under development). For
questions, further information or scheduling please contact
Christine DeFrancisco or Melissa Bastawros at (760) 598-1700.
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